{"symbol":"ADGRG1","synonyms":["TM7LN4","BPPR","BFPP","GPR56","TM7XN1"],"name":"adhesion G protein-coupled receptor G1","description":"This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]","ncbiEntrezGeneId":9289,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9289","proteins":[{"symbol":"GPR56_HUMAN","href":"/api/1.0/protein/GPR56_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}