{"symbol":"ADGRL3","synonyms":["LPHN3","LEC3","CIRL3","CL3"],"name":"adhesion G protein-coupled receptor L3","description":"This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":23284,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/23284","proteins":[{"symbol":"LPHN3_HUMAN","href":"/api/1.0/protein/LPHN3_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}