{"symbol":"ADH1B","synonyms":["HEL-S-117","ADH2"],"name":"alcohol dehydrogenase 1B (class I), beta polypeptide","description":"The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]","ncbiEntrezGeneId":125,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/125","proteins":[{"symbol":"ADH1B_HUMAN","href":"/api/1.0/protein/ADH1B_HUMAN"}],"hgncRootFamilies":[{"name":"Alcohol dehydrogenases (ADH)","href":"/api/1.0/gene_family/Alcohol+dehydrogenases+%28ADH%29"}]}