{"symbol":"ADORA1","synonyms":["RDC7"],"name":"adenosine A1 receptor","description":"The protein encoded by this gene is an adenosine receptor that belongs to the G-protein coupled receptor 1 family. There are 3 types of adenosine receptors, each with a specific pattern of ligand binding and tissue distribution, and together they regulate a diverse set of physiologic functions. The type A1 receptors inhibit adenylyl cyclase, and play a role in the fertilization process. Animal studies also suggest a role for A1 receptors in kidney function and ethanol intoxication. Transcript variants with alternative splicing in the 5\u0027 UTR have been found for this gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":134,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/134","proteins":[{"symbol":"AA1R_HUMAN","href":"/api/1.0/protein/AA1R_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}