{"symbol":"ADRB3","synonyms":["BETA3AR"],"name":"adrenoceptor beta 3","description":"The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. Obesity and bodyweight-related disorders are correlated with certain polymorphisms in three subtypes of beta-adrenoceptor, among them, the ADRB3 gene.[provided by RefSeq, Oct 2019]","ncbiEntrezGeneId":155,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/155","proteins":[{"symbol":"ADRB3_HUMAN","href":"/api/1.0/protein/ADRB3_HUMAN"}],"hgncRootFamilies":[{"name":"G protein-coupled receptors","href":"/api/1.0/gene_family/G+protein-coupled+receptors"}]}