{"symbol":"AES","synonyms":["AES-2","GRG","ESP1","AES-1","GRG5","TLE5","GRG-5"],"name":"amino-terminal enhancer of split","description":"The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":166,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/166","proteins":[{"symbol":"AES_HUMAN","href":"/api/1.0/protein/AES_HUMAN"}],"hgncRootFamilies":[]}