{"symbol":"AGO2","synonyms":["Q10","EIF2C2","CASC7"],"name":"argonaute RISC catalytic component 2","description":"This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in short-interfering-RNA-mediated gene silencing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]","ncbiEntrezGeneId":27161,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/27161","proteins":[{"symbol":"AGO2_HUMAN","href":"/api/1.0/protein/AGO2_HUMAN"}],"hgncRootFamilies":[{"name":"Argonaute/PIWI family (AGO, PIWIL)","href":"/api/1.0/gene_family/Argonaute%24slash%24PIWI+family+%28AGO%2C+PIWIL%29"}]}