{"symbol":"AGPS","synonyms":["ADAS","RCDP3","ADAP-S","ADHAPS","ALDHPSY","ADPS"],"name":"alkylglycerone phosphate synthase","description":"This gene is a member of the FAD-binding oxidoreductase/transferase type 4 family. It encodes a protein that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetonephosphate (DHAP) is converted to alkyl-DHAP by the addition of a long chain alcohol and the removal of a long-chain acid anion. The protein is localized to the inner aspect of the peroxisomal membrane and requires FAD as a cofactor. Mutations in this gene have been associated with rhizomelic chondrodysplasia punctata, type 3 and Zellweger syndrome. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":8540,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8540","proteins":[{"symbol":"ADAS_HUMAN","href":"/api/1.0/protein/ADAS_HUMAN"}],"hgncRootFamilies":[]}