{"symbol":"AGRP","synonyms":["AGRT","ART","ASIP2"],"name":"agouti related neuropeptide","description":"This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009]","ncbiEntrezGeneId":181,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/181","proteins":[{"symbol":"AGRP_HUMAN","href":"/api/1.0/protein/AGRP_HUMAN"}],"hgncRootFamilies":[{"name":"Endogenous ligands","href":"/api/1.0/gene_family/Endogenous+ligands"}]}