{"symbol":"AHR","synonyms":["BHLHE76"],"name":"aryl hydrocarbon receptor","description":"The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]","ncbiEntrezGeneId":196,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/196","proteins":[{"symbol":"AHR_HUMAN","href":"/api/1.0/protein/AHR_HUMAN"}],"hgncRootFamilies":[{"name":"Basic helix-loop-helix proteins (BHLH)","href":"/api/1.0/gene_family/Basic+helix-loop-helix+proteins+%28BHLH%29"}]}