{"symbol":"AIF1","synonyms":["AIF-1","IBA1","IRT-1","IRT1"],"name":"allograft inflammatory factor 1","description":"This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016]","ncbiEntrezGeneId":199,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/199","proteins":[{"symbol":"AIF1_HUMAN","href":"/api/1.0/protein/AIF1_HUMAN"}],"hgncRootFamilies":[{"name":"EF-hand domain containing","href":"/api/1.0/gene_family/EF-hand+domain+containing"}]}