{"symbol":"ALG12","synonyms":["ECM39","CDG1G","PP14673","HALG12"],"name":"ALG12, alpha-1,6-mannosyltransferase","description":"This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":79087,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/79087","proteins":[{"symbol":"ALG12_HUMAN","href":"/api/1.0/protein/ALG12_HUMAN"}],"hgncRootFamilies":[{"name":"Glycosyltransferases","href":"/api/1.0/gene_family/Glycosyltransferases"}]}