{"symbol":"ALG2","synonyms":["CDGII","CMSTA3","NET38","HALPG2","CMS14","CDG1I"],"name":"ALG2, alpha-1,3/1,6-mannosyltransferase","description":"This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]","ncbiEntrezGeneId":85365,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/85365","proteins":[{"symbol":"ALG2_HUMAN","href":"/api/1.0/protein/ALG2_HUMAN"}],"hgncRootFamilies":[{"name":"Glycosyltransferases","href":"/api/1.0/gene_family/Glycosyltransferases"}]}