{"symbol":"ALKBH3","synonyms":["ABH3","DEPC-1","hABH3","DEPC1"],"name":"alkB, alkylation repair homolog 3 (E. coli)","description":"The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 (MIM 610602) and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":221120,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/221120","proteins":[{"symbol":"ALKB3_HUMAN","href":"/api/1.0/protein/ALKB3_HUMAN"}],"hgncRootFamilies":[{"name":"Alkylation repair homologs (ALKBH)","href":"/api/1.0/gene_family/Alkylation+repair+homologs+%28ALKBH%29"}]}