{"symbol":"AMFR","synonyms":["GP78","RNF45"],"name":"autocrine motility factor receptor, E3 ubiquitin protein ligase","description":"This locus encodes a glycosylated transmembrane receptor. Its ligand, autocrine motility factor, is a tumor motility-stimulating protein secreted by tumor cells. The encoded receptor is also a member of the E3 ubiquitin ligase family of proteins. It catalyzes ubiquitination and endoplasmic reticulum-associated degradation of specific proteins. [provided by RefSeq, Feb 2012]","ncbiEntrezGeneId":267,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/267","proteins":[{"symbol":"AMFR_HUMAN","href":"/api/1.0/protein/AMFR_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}