{"symbol":"ANKS6","synonyms":["PKDR1","SAMD6","ANKRD14","NPHP16"],"name":"ankyrin repeat and sterile alpha motif domain containing 6","description":"This gene encodes a protein containing multiple ankyrin repeats and a SAM domain. It is thought that this protein may localize to the proximal region of the primary cilium, and may play a role in renal and cardiovascular development. Mutations in this gene have been shown to cause a form of nephronophthisis (NPHP16), a chronic tubulo-interstitial nephritis. [provided by RefSeq, Jul 2015]","ncbiEntrezGeneId":203286,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/203286","proteins":[{"symbol":"ANKS6_HUMAN","href":"/api/1.0/protein/ANKS6_HUMAN"}],"hgncRootFamilies":[{"name":"Sterile alpha motif (SAM) domain containing (SAMD)","href":"/api/1.0/gene_family/Sterile+alpha+motif+%28SAM%29+domain+containing+%28SAMD%29"},{"name":"Ankyrin repeat domain containing (ANKRD)","href":"/api/1.0/gene_family/Ankyrin+repeat+domain+containing+%28ANKRD%29"}]}