{"symbol":"ANO1","synonyms":["ORAOV2","TAOS2","TMEM16A","DOG1"],"name":"anoctamin 1, calcium activated chloride channel","description":"Enables identical protein binding activity; iodide transmembrane transporter activity; and ligand-gated monoatomic ion channel activity. Involved in several processes, including monoatomic anion transport; mucus secretion; and positive regulation of insulin secretion involved in cellular response to glucose stimulus. Located in apical plasma membrane and nucleoplasm. Implicated in Moyamoya disease. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":55107,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55107","proteins":[{"symbol":"ANO1_HUMAN","href":"/api/1.0/protein/ANO1_HUMAN"}],"hgncRootFamilies":[{"name":"Ion channels","href":"/api/1.0/gene_family/Ion+channels"}]}