{"symbol":"AP3B2","synonyms":["EIEE48","NAPTB"],"name":"adaptor-related protein complex 3, beta 2 subunit","description":"Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy. [provided by RefSeq, Feb 2017]","ncbiEntrezGeneId":8120,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8120","proteins":[{"symbol":"AP3B2_HUMAN","href":"/api/1.0/protein/AP3B2_HUMAN"}],"hgncRootFamilies":[]}