{"symbol":"APBA2","synonyms":["LIN-10","D15S1518E","HST16821","X11L","MGC:14091","MINT2","X11-BETA"],"name":"amyloid beta (A4) precursor protein-binding, family A, member 2","description":"The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer\u0027s disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer\u0027s disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2017]","ncbiEntrezGeneId":321,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/321","proteins":[{"symbol":"APBA2_HUMAN","href":"/api/1.0/protein/APBA2_HUMAN"}],"hgncRootFamilies":[]}