{"symbol":"APLF","synonyms":["C2ORF13","ZCCHH1","PALF","APFL","XIP1"],"name":"aprataxin and PNKP like factor","description":"Enables several functions, including ADP-D-ribose modification-dependent protein binding activity; nuclease activity; and poly-ADP-D-ribose binding activity. Involved in DNA repair; DNA repair-dependent chromatin remodeling; and protein localization to chromatin. Acts upstream of or within positive regulation of DNA ligation. Located in nucleoplasm. Is active in site of double-strand break. [provided by Alliance of Genome Resources, Mar 2025]","ncbiEntrezGeneId":200558,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/200558","proteins":[{"symbol":"APLF_HUMAN","href":"/api/1.0/protein/APLF_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"}]}