{"symbol":"APOBEC3G","synonyms":["ARP9","ARP-9","CEM-15","CEM15","MDS019","BK150C2.7","A3G","ARCD","DJ494G10.1"],"name":"apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G","description":"This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene catalyzes site-specific deamination of both RNA and single-stranded DNA. The encoded protein has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity. [provided by RefSeq, Mar 2017]","ncbiEntrezGeneId":60489,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/60489","proteins":[{"symbol":"ABC3G_HUMAN","href":"/api/1.0/protein/ABC3G_HUMAN"}],"hgncRootFamilies":[{"name":"Apolipoprotein B mRNA editing enzyme, catalytic polypeptides (APOBEC)","href":"/api/1.0/gene_family/Apolipoprotein+B+mRNA+editing+enzyme%2C+catalytic+polypeptides+%28APOBEC%29"}]}