{"symbol":"APOL3","synonyms":["CG121","APOL-III","APOLIII","CG12_1"],"name":"apolipoprotein L, 3","description":"This gene is a member of the apolipoprotein L gene family, and it is present in a cluster with other family members on chromosome 22. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids, including cholesterol, and/or allow the binding of lipids to organelles. In addition, expression of this gene is up-regulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]","ncbiEntrezGeneId":80833,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/80833","proteins":[{"symbol":"APOL3_HUMAN","href":"/api/1.0/protein/APOL3_HUMAN"}],"hgncRootFamilies":[{"name":"Apolipoproteins (APO)","href":"/api/1.0/gene_family/Apolipoproteins+%28APO%29"}]}