{"symbol":"ARF3","synonyms":[],"name":"ADP-ribosylation factor 3","description":"ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. [provided by RefSeq, Oct 2022]","ncbiEntrezGeneId":377,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/377","proteins":[{"symbol":"ARF3_HUMAN","href":"/api/1.0/protein/ARF3_HUMAN"}],"hgncRootFamilies":[{"name":"Ras small GTPases superfamily","href":"/api/1.0/gene_family/Ras+small+GTPases+superfamily"}]}