{"symbol":"ARHGAP29","synonyms":["PARG1"],"name":"Rho GTPase activating protein 29","description":"Rap1 is a small GTPase that, through effectors, regulates Rho GTPase signaling. These effectors- Rasip1, Radil, and the protein encoded by this gene- translocate to the cell membrane, where they form a multiprotein complex. This complex is necessary for Rap1-induced inhibition of Rho signaling. Defects in this gene may be a cause of nonsyndromic cleft lip with or without cleft palate. [provided by RefSeq, Jun 2016]","ncbiEntrezGeneId":9411,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9411","proteins":[{"symbol":"RHG29_HUMAN","href":"/api/1.0/protein/RHG29_HUMAN"}],"hgncRootFamilies":[{"name":"Rho GTPase activating proteins (ARHGAP)","href":"/api/1.0/gene_family/Rho+GTPase+activating+proteins+%28ARHGAP%29"}]}