{"symbol":"ARHGEF10","synonyms":["GEF10","SNCV"],"name":"Rho guanine nucleotide exchange factor (GEF) 10","description":"This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]","ncbiEntrezGeneId":9639,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/9639","proteins":[{"symbol":"ARHGA_HUMAN","href":"/api/1.0/protein/ARHGA_HUMAN"}],"hgncRootFamilies":[{"name":"Rho guanine nucleotide exchange factors (ARHGEF)","href":"/api/1.0/gene_family/Rho+guanine+nucleotide+exchange+factors+%28ARHGEF%29"}]}