{"symbol":"ARID4B","synonyms":["RBBP1L1","BCAA","SAP180","BRCAA1","RBP1L1"],"name":"AT rich interactive domain 4B (RBP1-like)","description":"This gene encodes a protein with sequence similarity to retinoblastoma-binding protein-1. The encoded protein is a subunit of the histone deacetylase-dependant SIN3A transcriptional corepressor complex, which functions in diverse cellular processes including proliferation, differentiation, apoptosis, oncogenesis, and cell fate determination. The gene product is recognized by IgG antibody isolated from a breast cancer patient and appears to be a molecular marker associated with a broad range of human malignancies. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":51742,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/51742","proteins":[{"symbol":"ARI4B_HUMAN","href":"/api/1.0/protein/ARI4B_HUMAN"}],"hgncRootFamilies":[{"name":"AT rich interactive domain containing (ARID)","href":"/api/1.0/gene_family/AT+rich+interactive+domain+containing+%28ARID%29"}]}