{"symbol":"ARID5B","synonyms":["DESRT","MRF-2","MRF2"],"name":"AT rich interactive domain 5B (MRF1-like)","description":"This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]","ncbiEntrezGeneId":84159,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/84159","proteins":[{"symbol":"ARI5B_HUMAN","href":"/api/1.0/protein/ARI5B_HUMAN"}],"hgncRootFamilies":[{"name":"AT rich interactive domain containing (ARID)","href":"/api/1.0/gene_family/AT+rich+interactive+domain+containing+%28ARID%29"}]}