{"symbol":"ARMC10","synonyms":["PNAS-112","SVH","PNAS112","PSEC0198"],"name":"armadillo repeat containing 10","description":"This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3. [provided by RefSeq, Sep 2011]","ncbiEntrezGeneId":83787,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/83787","proteins":[{"symbol":"ARM10_HUMAN","href":"/api/1.0/protein/ARM10_HUMAN"}],"hgncRootFamilies":[{"name":"Armadillo repeat containing (ARMC)","href":"/api/1.0/gene_family/Armadillo+repeat+containing+%28ARMC%29"}]}