{"symbol":"ARPC4","synonyms":["ARC20","P20-ARC"],"name":"actin related protein 2/3 complex, subunit 4, 20kDa","description":"This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3 (TTLL3), which results in the production of a fusion protein. [provided by RefSeq, Nov 2010]","ncbiEntrezGeneId":10093,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10093","proteins":[{"symbol":"ARPC4_HUMAN","href":"/api/1.0/protein/ARPC4_HUMAN"}],"hgncRootFamilies":[{"name":"Actin related protein 2/3 complex subunits (ARPC)","href":"/api/1.0/gene_family/Actin+related+protein+2%24slash%243+complex+subunits+%28ARPC%29"}]}