{"symbol":"ARRDC3","synonyms":["TLIMP"],"name":"arrestin domain containing 3","description":"This gene encodes a member of the arrestin family of proteins, which regulate G protein-mediated signaling. The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4, a tumor-related antigen, targeting the integrin for internalization and degradation. [provided by RefSeq, Jul 2016]","ncbiEntrezGeneId":57561,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/57561","proteins":[{"symbol":"ARRD3_HUMAN","href":"/api/1.0/protein/ARRD3_HUMAN"}],"hgncRootFamilies":[]}