{"symbol":"ARSB","synonyms":["MPS6","G4S"],"name":"arylsulfatase B","description":"Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targeted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2016]","ncbiEntrezGeneId":411,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/411","proteins":[{"symbol":"ARSB_HUMAN","href":"/api/1.0/protein/ARSB_HUMAN"}],"hgncRootFamilies":[{"name":"Sulfatases (ARS)","href":"/api/1.0/gene_family/Sulfatases+%28ARS%29"}]}