{"symbol":"ATG10","synonyms":["APG10L","PP12616","APG10"],"name":"autophagy related 10","description":"Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008]","ncbiEntrezGeneId":83734,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/83734","proteins":[{"symbol":"ATG10_HUMAN","href":"/api/1.0/protein/ATG10_HUMAN"}],"hgncRootFamilies":[]}