{"symbol":"ATG4C","synonyms":["APG4-C","APG4C","AUTL3"],"name":"autophagy related 4C, cysteine peptidase","description":"Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":84938,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/84938","proteins":[{"symbol":"ATG4C_HUMAN","href":"/api/1.0/protein/ATG4C_HUMAN"}],"hgncRootFamilies":[]}