{"symbol":"ATP4A","synonyms":["ATP6A"],"name":"ATPase, H+/K+ exchanging, alpha polypeptide","description":"The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes a catalytic alpha subunit of the gastric H+, K+-ATPase. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":495,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/495","proteins":[{"symbol":"ATP4A_HUMAN","href":"/api/1.0/protein/ATP4A_HUMAN"}],"hgncRootFamilies":[{"name":"ATPases","href":"/api/1.0/gene_family/ATPases"}]}