{"symbol":"ATP5I","synonyms":["ATP5K","ATP5ME"],"name":"ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E","description":"Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the e subunit of the Fo complex. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]","ncbiEntrezGeneId":521,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/521","proteins":[{"symbol":"ATP5I_HUMAN","href":"/api/1.0/protein/ATP5I_HUMAN"}],"hgncRootFamilies":[{"name":"ATPases","href":"/api/1.0/gene_family/ATPases"},{"name":"Mitochondrial respiratory chain complexes","href":"/api/1.0/gene_family/Mitochondrial+respiratory+chain+complexes"}]}