{"symbol":"B3GNT3","synonyms":["HP10328","B3GAL-T8","TMEM3","BETA3GN-T3","B3GNT-3","B3GN-T3"],"name":"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3","description":"This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein and contains a signal anchor that is not cleaved. It prefers the substrates of lacto-N-tetraose and lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains and the biosynthesis of the backbone structure of dimeric sialyl Lewis a. It plays dominant roles in L-selectin ligand biosynthesis, lymphocyte homing and lymphocyte trafficking. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":10331,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/10331","proteins":[{"symbol":"B3GN3_HUMAN","href":"/api/1.0/protein/B3GN3_HUMAN"}],"hgncRootFamilies":[{"name":"Glycosyltransferases","href":"/api/1.0/gene_family/Glycosyltransferases"}]}