{"symbol":"BACH1","synonyms":["BTBD24","BACH-1"],"name":"BTB and CNC homology 1, basic leucine zipper transcription factor 1","description":"This gene encodes a transcription factor that belongs to the cap\u0027n\u0027collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, May 2009]","ncbiEntrezGeneId":571,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/571","proteins":[{"symbol":"BACH1_HUMAN","href":"/api/1.0/protein/BACH1_HUMAN"}],"hgncRootFamilies":[{"name":"Basic leucine zipper proteins","href":"/api/1.0/gene_family/Basic+leucine+zipper+proteins"},{"name":"BTB (POZ) domain containing (BTBD)","href":"/api/1.0/gene_family/BTB+%28POZ%29+domain+containing+%28BTBD%29"}]}