{"symbol":"BAK1","synonyms":["CDN1","BCL2L7","BAK","BAK-LIKE"],"name":"BCL2-antagonist/killer 1","description":"The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":578,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/578","proteins":[{"symbol":"BAK_HUMAN","href":"/api/1.0/protein/BAK_HUMAN"}],"hgncRootFamilies":[]}