{"symbol":"BAMBI","synonyms":["NMA"],"name":"BMP and activin membrane-bound inhibitor","description":"This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":25805,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/25805","proteins":[{"symbol":"BAMBI_HUMAN","href":"/api/1.0/protein/BAMBI_HUMAN"}],"hgncRootFamilies":[]}