{"symbol":"BANK1","synonyms":["BANK"],"name":"B-cell scaffold protein with ankyrin repeats 1","description":"The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]","ncbiEntrezGeneId":55024,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/55024","proteins":[{"symbol":"BANK1_HUMAN","href":"/api/1.0/protein/BANK1_HUMAN"}],"hgncRootFamilies":[{"name":"Ankyrin repeat domain containing (ANKRD)","href":"/api/1.0/gene_family/Ankyrin+repeat+domain+containing+%28ANKRD%29"}]}