{"symbol":"BCL2L12","synonyms":[],"name":"BCL2-like 12 (proline rich)","description":"This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]","ncbiEntrezGeneId":83596,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/83596","proteins":[{"symbol":"B2L12_HUMAN","href":"/api/1.0/protein/B2L12_HUMAN"}],"hgncRootFamilies":[]}