{"symbol":"BCL7A","synonyms":["BCL7"],"name":"B-cell CLL/lymphoma 7A","description":"This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":605,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/605","proteins":[{"symbol":"BCL7A_HUMAN","href":"/api/1.0/protein/BCL7A_HUMAN"}],"hgncRootFamilies":[]}