{"symbol":"BDH1","synonyms":["BDH","SDR9C1"],"name":"3-hydroxybutyrate dehydrogenase, type 1","description":"This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":622,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/622","proteins":[{"symbol":"BDH_HUMAN","href":"/api/1.0/protein/BDH_HUMAN"}],"hgncRootFamilies":[{"name":"Short chain dehydrogenase/reductase superfamily (SDR)","href":"/api/1.0/gene_family/Short+chain+dehydrogenase%24slash%24reductase+superfamily+%28SDR%29"}]}