{"symbol":"BECN1","synonyms":["VPS30","ATG6","BECLIN1"],"name":"beclin 1, autophagy related","description":"This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]","ncbiEntrezGeneId":8678,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/8678","proteins":[{"symbol":"BECN1_HUMAN","href":"/api/1.0/protein/BECN1_HUMAN"}],"hgncRootFamilies":[]}