{"symbol":"BEX2","synonyms":["BEX1","DJ79P11.1"],"name":"brain expressed X-linked 2","description":"This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]","ncbiEntrezGeneId":84707,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/84707","proteins":[{"symbol":"BEX2_HUMAN","href":"/api/1.0/protein/BEX2_HUMAN"}],"hgncRootFamilies":[]}