{"symbol":"BIRC2","synonyms":["HIAP2","HIAP-2","API1","MIHB","C-IAP1","RNF48","CIAP1"],"name":"baculoviral IAP repeat containing 2","description":"The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]","ncbiEntrezGeneId":329,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/329","proteins":[{"symbol":"BIRC2_HUMAN","href":"/api/1.0/protein/BIRC2_HUMAN"}],"hgncRootFamilies":[{"name":"Zinc fingers","href":"/api/1.0/gene_family/Zinc+fingers"},{"name":"Baculoviral IAP repeat containing (BIRC)","href":"/api/1.0/gene_family/Baculoviral+IAP+repeat+containing+%28BIRC%29"}]}