{"symbol":"BLK","synonyms":["MODY11"],"name":"BLK proto-oncogene, Src family tyrosine kinase","description":"This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010]","ncbiEntrezGeneId":640,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/640","proteins":[{"symbol":"BLK_HUMAN","href":"/api/1.0/protein/BLK_HUMAN"}],"hgncRootFamilies":[{"name":"SH2 domain containing","href":"/api/1.0/gene_family/SH2+domain+containing"}]}