{"symbol":"BMF","synonyms":[],"name":"Bcl2 modifying factor","description":"The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":90427,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/90427","proteins":[{"symbol":"BMF_HUMAN","href":"/api/1.0/protein/BMF_HUMAN"}],"hgncRootFamilies":[]}