{"symbol":"BTG1","synonyms":["APRO2"],"name":"B-cell translocation gene 1, anti-proliferative","description":"This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]","ncbiEntrezGeneId":694,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/694","proteins":[{"symbol":"BTG1_HUMAN","href":"/api/1.0/protein/BTG1_HUMAN"}],"hgncRootFamilies":[]}