{"symbol":"C4BPA","synonyms":["PRP","C4BP"],"name":"complement component 4 binding protein, alpha","description":"This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. [provided by RefSeq, Jul 2008]","ncbiEntrezGeneId":722,"ncbiEntrezGeneUrl":"http://www.ncbi.nlm.nih.gov/gene/722","proteins":[{"symbol":"C4BPA_HUMAN","href":"/api/1.0/protein/C4BPA_HUMAN"}],"hgncRootFamilies":[]}